Cancers, unfortunately, are difficult to treat. And more and more people learn about their deplorable state already at those stages when the chance of recovery or remission is very low. However, there is a drug that contributes to the destruction of cancer cells. The remedy is called “Refnot.” The doctors' comments about the drug speak for themselves.
Pharmacological group
"Refnot", the opinions of doctors about which are very different, belong to the group of antitumor drugs. Many oncologists have successfully used the drug to treat a wide variety of tumor diseases. Including cancer of the stomach, intestines, lungs.
Release form
The drug “Refnot” is produced in the form of an injection preparation for further subcutaneous administration. The active substance is called leophysiliate. No other form of release simply exists. Therefore, if somewhere there is an offer to purchase a drug in the form of tablets or sprays, potions and other things, then with a 100% guarantee we can say that this is pure water fraud .
Manufacturing firm
The drug is available in Russia. Actually, it was also invented and patented on the territory of the Russian Federation. The drug "Refnot" was developed, reviews of which will be somewhat lower in 2002. The company that conducted the experiment, research and release is Pharmaclon. And only after that, in 2006, the patent was transferred to Refnot-Pharm. And only then the drug received wide publicity and began to be sold according to recipes. Until 2006, it was only offered as an experimental tool for cancer patients. The drug was tested at different stages of the disease, which made it possible to identify its strengths and weaknesses.
Side effects
Speaking about such a drug as "Refnot", the reviews of doctors about which are very controversial, one cannot but say about its weaknesses. In particular, about side effects. So, they include a temporary temperature increase of 1-3 degrees from the norm, increased sensitivity, which can develop with the use of the drug. In addition, during the first application, redness or irritation at the injection site may be noted. As a rule, after a day, all side effects disappear by themselves. In some cases, Ibuprofen is necessary to normalize body temperature.
When to take
It is noted that the drug shows the best result when it is used to treat cancer of the breast at different stages. Naturally, no one can guarantee full recovery at the last stage of cancer development and the spread of metastases throughout the body, but the patient is able to improve the patient’s condition. In particular, with symptomatic treatment, when therapy is aimed not at fighting the tumor, but at alleviating the pain syndrome of this disease. In addition, during chemotherapy more and more oncologists recommend the use of Refnot. True or false about the miraculous effect of the drug, it is difficult to understand.
Is it worth hoping for a miracle?
A rare doctor will reassure the patient or his relatives with very optimistic forecasts. As well as pessimistic. Most often, oncologists try to dryly state the facts. That is why it is very difficult to understand whether "Refnot" (the truth or a lie about a panacea in the form of this drug) really helps people. Speaking of cancer, one cannot be 100 percent sure that a particular remedy or method of treatment will be effective. Most often, the disease develops unpredictably, anything can provoke its spread. However, one should always hope for a miracle, otherwise it will never happen.
Drug action
Manufacturers claim that the drug has a direct in vivo and in vitro antitumor effect that destroys malignant cancer cells at different levels. As a result, the drug can be used at any stage of the disease. However, as it turned out, "Refnot" is not very effective in the treatment of gastric cancer 4st. Reviews about the use are not the most positive, but it is noted that the pain syndrome is significantly reduced. Therefore, you can still use the drug if there is such an opportunity and a doctor’s recommendation. Moreover, the toxicity of Refnot is one hundred times lower than that of TNF.
Efficiency
When testing the drug, it was noted that it increases the effectiveness of chemotherapy. In particular, drugs such as:
- "Cytosar";
- Actinomycin D;
- "5-fluorouracil."
All these drugs are difficult enough to penetrate the body, positively and at the same time negatively affecting it. "Refnot", the reviews of doctors which are similar in this matter, allows you to eliminate resistance. That is, it can and preferably be used in chemotherapy to increase its effectiveness, and most importantly - to reduce the number of its applications. The body receives many times less toxic substances that slow down the growth and development of cancer cells.
Test
Long before the drug was put into use, clinical trials and all kinds of experiments were conducted in Moscow and St. Petersburg. Testing was carried out on cancer cells of various stages. In Moscow, the N.N. Blokhin Russian Cancer Research Center conducted clinical trials of the first phase, where it was revealed that the drug has very low toxicity. As a result, initial reviews of the "Refnote" turned out to be positive among doctors. Clinical trials were conducted on squamous cell carcinoma of the head and neck, which is important. Subsequently, in St. Petersburg, the N.N. Petrov Oncology Research Institute conducted further testing at the second and third stages of cancer. In particular, locally advanced and metastatic breast cancer in combination with chemotherapy. And here the drug showed brilliant results. After that, feedback on the action of "Refnota" became even better.
Study Treatment Groups
In order to find out how effective the drug was, people were selected (in both the first and second trials), united by special factors. In particular, these are:
- Life expectancy. She should have been at least three months old.
- Age. He should not have been more than 75 years old.
- The consent of the patient himself. Not everyone in this state is ready to take risks.
- General state. It should have been between 0-2 WHO.
- Full confirmation of the diagnosis made earlier.
Injections with the drug were administered daily at a dosage of 100,000 IU. Moreover, for each patient there was an individual way of dosing the drug. For example, an injection (100,000 IU) was required before a course of chemotherapy. In general, the drug worked well at different stages of the disease, so the research was continued. It is worth noting that the patients who participated in the experiment were able to prolong life, and most importantly, to slow down the growth of cancer cells.
Research result
After the clinical trials were completed, all doctors unanimously agreed that the most effective drug was in the treatment of breast cancer in combination with chemotherapy. That is why today it is recommended in such cases, almost ignoring everyone else. That is why "Refnot" is so ineffective in the treatment of gastric cancer 4st. Reviews about this are not only from close patients, but also from the doctors themselves. They were the first to note the almost complete ineffectiveness of the drug with such a disease. Later, it became clear to the people themselves that "Refnot" is not a panacea, but only one of the possible medicines that should not necessarily help.
Is it worth it to apply?
If an oncologist strongly recommends using Refnot to slow the spread of the disease, you still need to listen to his advice. In most cases, specialists know much better what can help at one stage or another of a cancerous tumor. In addition, the opinions of doctors themselves about the drug, although contradictory, are similar in one - simply cannot be found with other chemotherapy. "Refnot" is almost non-toxic, has minor side effects, has been produced and tested by Russian experts, has no analogues in the world, which means there is no reason to distrust it. If there is a corresponding recommendation of the attending physician, then you need to use the medicine. Especially when it comes to breast cancer, which is treated with chemotherapy drugs.