Absolutely all suffer from colds, and in the spring-autumn period this is felt especially sharply. To quickly get rid of a sore throat and speed up recovery, many people recommend Grammidin. Reviews about it in most cases are positive, and what are the features of the medication, described below.
Composition and release forms
The main active ingredient of any form of the drug is an antibiotic - gramicidin C. In each tablet for resorption for adults, 1.5 mg of the substance is concentrated. Auxiliary components are sucrose, milk sugar, calcium stearate and methyl cellulose.
Grammidin with an anesthetic and Grammidin NEO are also available for adults.
In the first form of release, 10 mg of lidocaine hydrochloride is additionally included in the composition. In addition, the drug contains citric acid, menthol and eucalyptus oil. The release form of NEO resorption tablets is characterized by an increased dosage of the active substance of 3 mg. An additional substance is 1 mg of cetylpyridinium chloride.
Tablets are produced in cardboard boxes with two blisters of 9 tablets in each and instructions for use. Reviews of "Grammidine" for frequent diseases recommend purchasing the drug immediately in plastic jars, also packed in cardboard boxes. There is more medicine in such a container, and the price for it is more favorable.
Recently, another form of the drug has appeared on sale - the Grammidin spray. Reviews about it are still few in number, but they already help to form a clear picture of the effectiveness of the drug. The drug is also based on gramicidin C, which in a single dose contains 0.06 mg. As auxiliary components, the composition includes purified water, ethanol, glycerol, polysorbate, flavors, sodium citrate and other substances.
Medicine for children
It is possible to use resorption tablets in treatment only from the age of 12, and the spray from 18 years of age, therefore, if necessary, therapy of young patients should buy a release form for children.
You can use it from 4 years. According to reviews, "Grammidin Children's" practically does not cause allergic reactions, but since it is also based on an antibiotic, it should be used without exceeding the recommended dosage (this is for the safety of the child). In addition to gramicidin C, the composition contains an antiseptic component, cetylpyridinium chloride. For children, the drug is made only in the form of lozenges.
Drug action
The main active substance of the drug has a bactericidal effect due to the fact that it changes the degree of permeability of the cell membranes of gram-positive and gram-negative bacteria. This effect is observed with almost all pathogens of infectious diseases of the pharynx and inflammatory processes of the oral mucosa. When the walls of the pathogen cells are damaged, the microorganism dies almost immediately. According to reviews, Grammidin is completely non-addictive, and these opinions are expressed by many experts.
The antiseptic effect of the drug is due to the presence of cetylpyridinium chloride in any form of release. This substance inhibits the reproduction and growth of bacteria in the oral cavity. The antimicrobial and antiseptic effect of the medication is also enhanced by excessive salivation during resorption. This natural process promotes active mechanical cleansing of the pharynx and oral cavity.
In addition to direct treatment, according to the instructions, Grammidin (reviews confirm the information) also has an instant analgesic effect. Local anesthesia is provided by the substance oxybuprocaine (due to blocking of nerve impulses).
Thus, the drug helps not only accelerate recovery and get rid of pathogenic microflora in the throat, but also alleviate the patient’s condition by relieving pain.
Recommendations for use
According to the action of the drug described above, it is easy to guess that it is aimed at treating sore throat caused by various causes, and inflammation in the oral cavity. The most common diagnoses for using Grammidine are:
- acute and chronic tonsillitis;
- acute pharyngitis of any etiology;
- gingivitis;
- angina;
- stomatitis;
- periodontitis;
- periodontal disease and other ailments.
Dosage and application
According to the instructions and reviews, Grammidin should be taken after meals. Patients explain this need very simply - after resorption of the pill or irrigation of the throat with a spray, you should not eat or drink for 1-2 hours and (in order not to remain hungry) it is better to eat right away. The drug is distinguished by local effects, so it practically does not enter the digestive system and has a therapeutic effect, only being in direct contact with inflamed areas.
In order for the use of the medication to be effective, chewing tablets is prohibited. Their resorption promotes profuse salivation and better purification of the mucous membranes from pathogenic microflora.
The usual "Grammidin" can be used in the treatment of patients from 12 years old. Once you should dissolve 2 tablets in turn with a break of half an hour. There should be no more than four such procedures per day.
As for the spray, it should be applied three times a day, irrigating the inflamed mucous membranes with four sprays at a time.
"Grammidin for children" instructions and reviews are recommended to be taken according to the same rules. The maximum daily dosage in this case is 4 tablets. Multiplicity of reception - 4 times.
The course of treatment with the drug should be seven days. If during this time there is no relief or symptoms worsen, you should consult a specialist.
Drug interaction
The drug is a tool for local treatment, therefore, it is almost always used as part of complex therapy. “Grammidin” is not in vain that the reviews of doctors are positioned as an effective remedy for serious inflammations. The fact is that its main active substance is able to enhance the effect of other antibiotics that can be prescribed systemically. Thus, the drug helps to overcome serious bacterial infections not only by its direct effect, but also by the activation of other medications.
Possible negative consequences
According to reviews, Grammidin is very well tolerated by most patients. Even in children, the appearance of negative reactions is a rarity, but you should be prepared for the fact that the body will not take the medicine and show an allergic reaction. Possible symptoms include skin rashes.
In addition, in especially sensitive people, the anesthetic effect can manifest itself very strongly, which provokes temporary numbness of the tongue.
In case of an overdose, reactions from the digestive system in the form of vomiting, nausea, or diarrhea can occur.
Bans to use
The main contraindication to the drug is personal intolerance to any of the components of the composition. Since different substances act in different forms of release as additional ingredients, intolerance can manifest itself only on tablets or only on spray. It is forbidden to use Grammidin in the treatment of pregnant and lactating women, as well as children under the age of 4 years.
Drug storage
Store the drug in a place inaccessible to children and direct sunlight at a temperature not exceeding 25 degrees. Subject to all conditions, the shelf life of the tablets is 3 years, and the spray is 2 years. After the expiration of the period, the product must be disposed of.
Analogues of the drug
According to the active substance, only "Gramitsidin S" can be distinguished among the modern range of medicines. This drug has the disadvantage of a lack of anesthetic in the composition and the presence of sucrose in it. The advantage of the medication is its low cost and the possibility of use in children aged 2 years.
According to reviews, Grammidin has analogues in terms of its therapeutic effect. Among them are almost all popular remedies for sore throat. Most often, patients are interested in how effective Grammidin is compared with Faringosept and Lizobakt. The first medication is also based on a bactericidal substance, but at the same time it is not an antibiotic, that is, it has less effectiveness, but it costs less. "Lizobakt" is an antiseptic, approved for pregnant women and children from 3 years old, but also does not have an antibiotic. If there is no need to use such a strong bactericidal agent, the drug can be safely replaced with Stopangin, Hexoral, Kameton, Furatsilin, Miramistin, Fervex for sore throat medicines and other drugs. Among antibiotics, medicines have a similar effect:
- "Flemoklav Solyutab";
- "Bicillin 3";
- Sumamed Forte;
- "Bicillin 5" and others.
Reviews
Grammidin collects positive reviews from adult patients because it has a strong anesthetic effect. Some argue that the drug does not provide the treatment itself or it manifests itself very weakly, but due to the analgesic effect they continue to take the drug. As an independent solution to the problem of inflammation, Grammidin is used very rarely. Most often, the drug is a component of complex therapy along with Furacilin, Miramistin, or another rinse.
Grammidin for children collects reviews of parents even more mixed. Some adults are confident in its effectiveness. The drug helped their children get rid of serious inflammation in the throat in just 7 days, and most importantly, after using it, the ailments did not return for a long time. Among the advantages it should be noted and the pleasant taste of the tablets, which allows you to treat even the most harmful babies without problems. The cost of the drug can not be called low, but given the fact that the packaging is always enough for the full course of treatment, and sometimes it remains a little the next time, the price is justified.
Along with a large number of such positive opinions, opposing opinions are often found. In some children, the drug causes bright allergic reactions in the form of a skin rash, and even in those who are not very sensitive. Of course, such cases cannot be called frequent, especially since the instruction immediately warns about individual intolerance and possible consequences. Among those dissatisfied with the effect of the medication there are those who consider it completely ineffective. This effect is also due to the individual characteristics of the body and simply requires the replacement of the drug.
Conclusion
Despite the low sensitivity to the active substance in some patients, the drug is considered the most effective in the treatment of throat diseases. This is due to the presence of an antibiotic in the composition, which has a strong bactericidal effect. Grammidin is also distinguished from its direct analogue by the presence of an anesthetic in the composition, which gives it a definite advantage for both adults and children.