B vitamins are natural substances that enter the human body along with food. They are extremely important for natural life. The main goal of these vitamins is the normal activity of the nervous system. If an insufficient amount of them enters the human body, then this may ultimately lead to interruptions in the activity of the nervous system. In addition, when destructive processes occur in the nervous system, B vitamins in tablets and injections have a therapeutic effect because of their ability to influence the metabolism and reconstruct nerve fibers. For this reason, this group of drugs is often used in the treatment of neurological diseases.
Over the past ten years, they began to be used for disorders in any part of the nervous system, since it was proved that the role of vitamin B deficiency is manifested in impaired thinking. This article will describe the main aspects of the use of B vitamins in the neurological field.
The most important vitamins
Three of them are among the most important:
- B1 vitamins (thiamine);
- B6 vitamins (pyridoxine);
- B12 vitamins (cyanocobalamin).
They are indispensable for our nerves and brain. Group B vitamins for hair are also very beneficial.
Vitamins from this group are not equivalent in their effect. Each of them has its own tasks. Consider each of the B vitamins in more detail.
Vitamin B1
B1 affects the following factors:
- creates the conditions for the transformation of carbohydrates into nerve cells, reinforcing its energy potential;
- performs important functions to conduct nerve impulses along the peripheral processes of nerve cells, thereby transmitting an impulse;
- conducts the construction of membranes of nerve cells;
- takes part in the restoration of destroyed nerve processes (regeneration).
Vitamin B6 Functions
B6 performs the following functions:
- is present in the synthesis and destruction of biologically active substances involved in the transmission of information to the nervous system (serotonin, dopamine, gamma-aminobutyric acid and others);
- improves fat metabolism and protein synthesis;
- participates in the transmission of impulses to the place of contact of two nerve cells;
- carries out the fight against free radicals, thereby it is an antioxidant.
The next vitamin of group B is B12.
The action of vitamin B12
It is necessary for:
- the construction of the myelin sheath of nerves;
- carries out the synthesis of acetylcholine (with the help of it there are transfer of impulses between neurons);
- reduction of pain symptoms that are associated with the destruction of nerve fibers.
But this is not all the important actions of the complex of vitamins of group B. Here is represented only a small part of their work, which applies only to the nervous system. It also has a great effect on the whole body.
Due to such an important activity of B vitamins in fulfilling metabolic functions in the nervous system, they are also called neurotropic.
Feature
They have a special property: with a single use, their effect becomes much higher than just the result of their individual effects. This means that a one-time appointment at a time of all three drugs is more effective than using them alone. About ten years ago, pharmaceutical companies turned their efforts to the formation of combined preparations of B vitamins. The names will be presented below. This was done in order to improve the quality of treatment and improve the usability of drugs. So, let's say, earlier it was necessary to perform three different injections in order for the patient to be able to receive all three neurotropic vitamins at once. But at the moment there are drugs containing all three components. After all, it is true that this is much more convenient and causes less discomfort to the patient. There are also a large number of B vitamins in tablets in pharmacies. We will describe the names of the drugs.
Neurological pathologies in the treatment of which these vitamins are used
The effect of B vitamins on the nervous system is poorly understood. Each time new information arrives after research. And each time with new studies, the list of neurological diseases on which neurotropic vitamins exert their therapeutic effect is constantly increasing. The list of neurological pathologies in which it will be possible to use B vitamins in injections consists of:
- different types of polyneuropathies (especially alcoholic and diabetic);
- neuropathy of single nerves (infectious and traumatic);
- neurological exacerbations of osteochondrosis of each of the spine (torcalgia, lumbalgia, cervicalgia, cervicalgia, thoracalgia, radicular syndromes);
- tunnel syndromes (tarsal canal syndrome and others);
- trigeminal neuralgia;
- neuropathic pains (postherpetic neuralgia) ;
- myelopathy
- multiple sclerosis;
- mental disabilities and certain types of dementia;
- pyridoxine-associated epilepsy in children.
The names of B vitamins in tablets are of interest to many.
Mechanism of action
The therapeutic effect is to stimulate the restoration of nerve fibers and membranes, increasing nerve conduction. Due to this, the severity of sensitive and motor disorders is reduced in patients. In addition, with the destruction of the nervous system, the use of vitamins of this group can achieve a good analgesic result in neuropathic pain. At the moment, a positive effect on vascular and neurodegenerative diseases has been proven.
There are scientific suggestions that, thanks to a multi-stage biochemical process, B vitamins in injections can slow the development of atherosclerosis and reduce the risk of thrombosis. Judging by this, their use may turn out to be useful, in particular, in the prevention of the appearance of cerebrovascular disorders (strokes).
How does a deficit arise?
It is also necessary to pay attention to the fact that most of the above pathologies of the nervous system in some cases can be reduced to a deficiency of their content in the body. At the same time, there are no other reasons for the manifestation of these diseases. Suppose polyneuropathy can occur on its own, but only in the presence of a deficiency of vitamin B1 or B6, and a long deficiency of vitamin B12 will cause damage to the spinal cord. With the help of studies it was found that a deficiency of vitamins B most often occurs with:
- malnutrition (since a person receives most of the vitamins with food);
- alcohol abuse (while nutrition may become unbalanced, and B1 is necessary for the body to break down alcohol);
- drug addiction (due to an antisocial lifestyle);
- impaired absorption in the intestines (peptic ulcer, malabsorption syndrome and other diseases);
- after surgical interventions on the digestive tract;
- with the use of certain medications (for example, diuretics for edema or Isoniazid for tuberculosis).
It is important that the therapeutic effects of group B vitamins in tablets and ampoules are carried out regardless of their deficiency.
Features of use
B vitamins appear to be water-soluble, which allows them to easily penetrate when taken and enter into a relationship with the natural environment of the body. Nevertheless, vitamin B1 in small doses in the form of tablets is destroyed in the intestine by enzymes, in accordance with this, it is not well absorbed. If you try to increase the dose, this can lead to a general blockage of the transition of the vitamin from the intestine to the blood. How to be here?
Experts have found a suitable way. The necessary concentrations can be achieved during parenteral administration, as well as using the fat-soluble form of vitamin B1. This type of vitamin B is also called Benfotiamine. This species is highly resistant to the influence of gastrointestinal enzymes, and therefore it is possible to achieve the correct assimilation of large doses and obtain the desired concentration of the drug in the blood.
The use of vitamins in combination
There is another feature of the use of preparations of B vitamins - separately taken B1, B6, B12 should not be used as a common injection with a single syringe, this refers to the mixture. Precisely because in the pharmacy these vitamins can be obtained only individually in ampoules B1, B6 and B12. In such cases, it is strongly forbidden to combine solutions from different ampoules in one syringe. But, since there is a frequent need for their combined use, pharmaceutical organizations have solved this problem. Mixtures of these vitamins were synthesized and already mixed in one ampoule, and they do not interfere with each other, but, on the contrary, improve the result of action. So, if there is an urgent need, all three components of the B vitamins in tablets and ampoules are prescribed immediately.
There are also mixtures that contain Lidocaine, an anesthetic. It provides an anesthetic effect and makes such an injection practically insensitive to the patient.
And another feature of the use of vitamins is that it is possible the manifestation of various allergic reactions to them. In general, each drug substance can create such an effect or cannot be tolerated individually by the patient, that is, it is impossible to predict which reaction will occur. Nevertheless, you need to be more careful especially with vitamins B1 and B12. An allergy to these vitamins can and is rare, but still this sometimes happens, so this fact must be taken into account both by the patient and the medical staff.
List
The business world has also affected the pharmaceutical industry. Regarding B vitamins, this happens in this way: the top three vitamins are represented by a large number of different drugs. Based on this, the same drugs with the same composition can have completely different actions. The difference is not only in the manufacturer, but also in the additional substances contained in the preparation, and of course, the differences in price. There are manufacturers who claim that the degree of purification affects the effectiveness of a particular drug. But you do not need to evaluate vitamins B only on this indicator. We define them only by type of release and composition. In order not to be mistaken for sure and not to overpay for the same substances as part of different drugs, it is recommended to familiarize yourself with the list below.
So, the most common injectable drugs are:
- "Vitaxon."
- "Binavit."
- The Milgamma.
- "Neurorubin."
- "Combilipen".
- "Neurobion."
- "Trigamma."
- Compligam B
These names of vitamins of group B are at everyone's hearing. What can they have in common? All of the above drugs are made in the form of solutions for intramuscular injection. In one ampoule of each of them contains 100 mg of B6, 100 mg of B1 and 1 g of B12. From this it can be seen that the active substances are absolutely identical in both composition and dosage. There are drugs containing in their composition an additional 20 mg of Lidocoin so that there is an analgesic effect (these are all of the above drugs, except for Neurorubin and Neurobion).
They have one more difference: “Neurorubin” and “Neurobion” contain 3 ml of solution in one ampoule, while others have 2 ml. Although this does not affect the total dose. In order to get an equal amount of mg of vitamins, you need to pierce, for example, “Neurobion” 3 ml and “Combilipen” 2 ml.
We also give the names of the preparations of B vitamins in tablets.
- "Doppelherz Asset" with magnesium and vitamins of group B. Bioadditive produced by a German pharmaceutical company. It has a positive effect on blood vessels, heart, nerve cells, restores vitality, stabilizes muscle function, strengthens the immune system. Dosage: 1 tablet per day. For packaging number 30 will have to pay 310 rubles.
- "Neurovitan" - perfectly treats muscle and nervous disorders. With pyridoxine, riboflavin, cyanocobalamin, octothiamine in the composition. It is actively absorbed from the digestive tract, has a prolonged effect. The product is safe and effective, suitable for children from 3 years old and pregnant. Indications are arthralgia, myalgia, intercostal neuralgia, and reduced immunity. During the day, from 1 to 4 tablets are taken. The average cost is 400 rubles.
- "Neuromultivitis." It has a high concentration of thiamine hydrochloride, cyanocobalamin and pyridoxine, for this reason it actively affects nerve cells and metabolism. It well treats shoulder-shoulder syndrome, intercostal neuralgia, spondylolisthesis, scoliosis, polyneuropathy, muscle and joint pain, lumbago with sciatica. Take 3 times a day for 1 unit. The cost is 250 rubles.
- "Neurobeks Neo" - in a composition with pyridoxine, calcium pantothenate, riboflavin, thiamine nitrate, folic acid, cyanocobalamin. Ascorbic and nicotinic acids complement the action. It is prescribed for spondylosis, polyneuritis, lumbago, arthralgia, myositis, myalgia, neuralgia, sciatica, chronic fatigue. You need to take a month, 3 times a day for 1 dragee. You can buy for 400 rubles.
- Kombilipen Tabs. Composed with pyridoxine hydrochloride, benfotiamine, cyanocobalamin. As a result of the reception, the work of the peripheral and central nervous system is normalized. The price is about 400 rubles.
The list of names of group B vitamins in tablets is extensive.
And, of course, the last word for the price. According to this indicator, all drugs are very different from each other. Preparations that were produced abroad will be much more expensive than domestic counterparts. It is better, of course, to buy such a preparation of B vitamins, which will have an affordable price.
I would also like to separately note that all these funds are medicines. Therefore, they are forbidden to take on their own and uncontrolled. Of course, these are vitamins, but they are presented in therapeutic dosages, and therefore, only a doctor can prescribe them. Especially when it comes to B vitamins in ampoules.
From the above, it is concluded that these drugs are used to combat various disorders of the nervous system. Group B vitamins for hair are also effective.
Conclusion
Today, doctors have a huge selection of medicines with the ability to choose certain dosages and different price categories, which is undoubtedly a big plus. And if we take into account that every day more and more information is opened about their actions, then we can assume that in the near future the list of these funds will be replenished with the latest drugs with a different composition and dosage.
We examined what constitutes a complex of vitamins of group B.